The Influenza Centre"> pub2000
PUBLICATIONS 2000 - 2009

Intramuscular Matrix-M-adjuvanted virosomal H5N1 vaccine induces high frequencies of multifunctional Th1 CD4+ cells and strong antibody responses in mice.
Madhun AS, Haaheim LR, Nilsen MV, Cox RJ.
Vaccine. 2009 Dec 9;27(52):7367-76.

A cell-based H7N1 split influenza virion vaccine confers protection in mouse and ferret challenge models.
Cox RJ, Major D, Hauge S, Madhun AS, Brokstad KA, Kuhne M, Smith J, Vogel FR, Zambon M, Haaheim LR, Wood J.
Influenza Other Respi Viruses. 2009 May;3(3):107-17.

A pilot study of the immune response to whole inactivated avian influenza H7N1 virus vaccine in mice.
Hovden AO, Brokstad KA, Major D, Wood J, Haaheim LR, Cox RJ.
Influenza Other Respi Viruses. 2009 Jan;3(1):21-8.

The immunogenicity of a cell-derived H7N1 split influenza virion vaccine in mice.
Hauge S, Madhun AS, Major D, Brokstad KA, Vogel FR, Zambon M, Wood J, Haaheim LR, Cox RJ.
Scand J Immunol. 2009 Jun;69(6):576-8.

A phase I clinical trial of a PER.C6 cell grown influenza H7 virus vaccine.
Cox RJ, Madhun AS, Hauge S, Sjursen H, Major D, Kuhne M, Höschler K, Saville M, Vogel FR, Barclay W, Donatelli I, Zambon M, Wood J, Haaheim LR.
Vaccine. 2009 Mar 18;27(13):1889-97.

Influenza: the virus and prophylaxis with inactivated influenza vaccine in "at risk" groups, including COPD patients.
Hovden AO, Cox RJ, Haaheim LR.
Int J Chron Obstruct Pulmon Dis. 2007;2(3):229-40. Review.

Local and systemic cytokine and chemokine responses after parenteral influenza vaccination.
Eriksson JC, Cox RJ, Szyszko E, Davidsson A, Brokstad KA.
Influenza Other Respi Viruses. 2007 Jul;1(4):139-46.

Quality and kinetics of the antibody response in mice after three different low-dose influenza virus vaccination strategies.
Hauge S, Madhun A, Cox RJ, Haaheim LR.
Clin Vaccine Immunol. 2007 Aug;14(8):978-83.

A comparison of the humoral and cellular immune responses at different immunological sites after split influenza virus vaccination of mice.
Hauge S, Madhun AS, Cox RJ, Brokstad KA, Haaheim LR.
Scand J Immunol. 2007 Jan;65(1):14-21.

Pandemic influenza vaccine development: time is of the essence.
Cox RJ, Brokstad KA, Haaheim LR.
Expert Rev Vaccines. 2006 Oct;5(5):603-6.

Impact of influenza vaccine formulation with a detailed analysis of the cytokine response.
Szyszko E, Brokstad K, Cox RJ, Hovden AO, Madhun A, Haaheim LR.
Scand J Immunol. 2006 Nov;64(5):467-75.

The humoral and cellular responses induced locally and systemically after parenteral influenza vaccination in man.
Cox RJ, Haaheim LR, Ericsson JC, Madhun AS, Brokstad KA.
Vaccine. 2006 Nov 10;24(44-46):6577-80.

The humoral immune response and protective efficacy of vaccination with inactivated split and whole influenza virus vaccines in BALB/c mice.
Cox RJ, Hovden AO, Brokstad KA, Szyszko E, Madhun AS, Haaheim LR.
Vaccine. 2006 Nov 10;24(44-46):6585-7.

Two doses of parenterally administered split influenza virus vaccine elicited high serum IgG concentrations which effectively limited viral shedding upon challenge in mice.
Hovden AO, Cox RJ, Madhun A, Haaheim LR.
Scand J Immunol. 2005 Oct;62(4):342-52. Erratum in: Scand J Immunol. 2005 Oct;62(4):420.

Whole influenza virus vaccine is more immunogenic than split influenza virus vaccine and induces primarily an IgG2a response in BALB/c mice.
Hovden AO, Cox RJ, Haaheim LR.
Scand J Immunol. 2005 Jul;62(1):36-44.

Influenza virus: immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines.
Cox RJ, Brokstad KA, Ogra P.
Scand J Immunol. 2004 Jan;59(1):1-15. Review.

Parenteral vaccination against influenza does not induce a local antigen-specific immune response in the nasal mucosa.
Brokstad KA, Eriksson JC, Cox RJ, Tynning T, Olofsson J, Jonsson R, Davidsson A.
J Infect Dis. 2002 Apr 1;185(7):878-84.

Non-lethal viral challenge of influenza haemagglutinin and nucleoprotein DNA vaccinated mice results in reduced viral replication.
Cox RJ, Mykkeltvedt E, Robertson J, Haaheim LR.
Scand J Immunol. 2002 Jan;55(1):14-23.

The effect of zanamivir treatment on the early immune response to influenza vaccination.
Cox RJ, Mykkeltvedt E, Sjursen H, Haaheim LR.
Vaccine. 2001 Sep 14;19(32):4743-9.

High prevalence of influenza specific antibody secreting cells in nasal mucosa.
Brokstad KA, Cox RJ, Eriksson JC, Olofsson J, Jonsson R, Davidsson A.
Scand J Immunol. 2001 Jul-Aug;54(1-2):243-7.